Physiology of the distal convoluted tubule and collecting duct
نویسندگان
چکیده
منابع مشابه
Renal Physiology Distal Convoluted Tubule
The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule regulates these processes at the molecular l...
متن کاملA functional comparison of the cortical collecting tubule and the distal convoluted tubule.
Electrical and permeability features of the distal convoluted tubule (DCT) and the cortical collecting tubule (CCT) were examined using the technique in which isolated segments of rabbit tubules were perfused in vitro. When rabbits were given a regular diet and tubules were perfused and bathed in artificial solutions simulating plasma ultrafiltrate, the potential difference (PD) was +3.7 plus o...
متن کاملPotassium transport in the distal tubule and collecting duct of the rat.
Because of recent conflicting results, micropuncture studies were performed to clarify the respective role of the distal convoluted tubule and collecting duct in the regulation of urinary potassium excretion. Five groups of Sprague-Dawley rats were studied: group I, hydropenia (n = 10); group II, Ringer loading (n = 7); group III, acute KC1 loading (n = 6); group IV, mannitol diuresis (n = 6); ...
متن کاملResponse of the distal tubule and cortical collecting duct to vasopressin in the rat.
Renal micropuncture observations in the rat suggest that the entire "distal tubule" (defined by the micropuncturist as that portion of the renal tubule extending between the macula densa and its first junction with another (renal tubule) may be responsive to vasopressin. However, this portion of the renal tubule contains two segments that are morphologically dissimilar. The "early" distal tubul...
متن کاملA new model of the distal convoluted tubule.
The Na(+)-Cl(-) cotransporter (NCC) in the distal convoluted tubule (DCT) of the kidney is a key determinant of Na(+) balance. Disturbances in NCC function are characterized by disordered volume and blood pressure regulation. However, many details concerning the mechanisms of NCC regulation remain controversial or undefined. This is partially due to the lack of a mammalian cell model of the DCT...
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ژورنال
عنوان ژورنال: Southern African Journal of Anaesthesia and Analgesia
سال: 2020
ISSN: 2220-1173,2220-1181
DOI: 10.36303/sajaa.2020.26.6.s3.2559